Gynec Cancers
Vulvar Cancer
Vulvar cancer is a rare form of cancer that occurs on the outer surface area of the female genitalia.
- ON THIS PAGE:
- Overview
- Signs & Symptoms
- Diagnosis
- Treatment
- FAQs
Overview of Vulvar Cancer
Vulvar cancer is a rare form of cancer that occurs on the outer surface area of the female genitalia. It primarily affects the vulva, which includes the labia majora, labia minora, clitoris, and the opening of the vagina.
It can develop in various types of cells found in the vulvar tissue, most commonly in the squamous cells that line the surface.
→ How Does Vulvar Cancer Occur?
Vulvar cancer begins when the cells in the vulvar tissue start to grow uncontrollably. These abnormal cells can form tumors and have the potential to spread (metastasize) to other parts of the body if not detected and treated early.
→ Factors Responsible for Vulvar Cancer
Several factors may increase the risk of developing vulvar cancer, including:
- Human Papillomavirus (HPV) Infection: A significant risk factor, as HPV is a common sexually transmitted infection.
- Age: Most cases occur in women over the age of 50.
- Smoking: Increases the risk of many cancers, including vulvar cancer.
- Chronic Vulvar Conditions: Conditions such as lichen sclerosus can increase the risk.
- Immunosuppression: A weakened immune system, due to conditions like HIV or medications that suppress immunity, can increase susceptibility.
→ Stages and Grades of Vulvar Cancer
- Stage I: Cancer is confined to the vulva or perineum. Prognosis is generally good with a high survival rate.
- Stage II: Cancer has spread to nearby structures such as the lower urethra, lower vagina, or anus. Prognosis remains favorable with appropriate treatment.
- Stage III: Cancer has spread to the lymph nodes but not to distant sites. Prognosis is more guarded and requires more aggressive treatment.
- Stage IV: Cancer has spread to the upper urethra, upper vagina, bladder, rectum, or distant organs. Prognosis is poor, and treatment focuses on managing symptoms and improving quality of life.
→ Grades of Vulvar Cancer
- Grade 1 (Low Grade): Cancer cells look similar to normal cells and grow slowly.
- Grade 2 (Intermediate Grade): Cancer cells look more abnormal and grow at a moderate rate.
- Grade 3 (High Grade): Cancer cells look very different from normal cells and grow quickly.
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Types of Cancers Associated with Vulvar Cancer
- Squamous Cell Carcinoma: The most common type, originating in the squamous cells lining the vulva.
- Adenocarcinoma: Originates in the glandular cells of the vulva.
- Melanoma: A rare type that starts in the pigment-producing cells.
- Sarcoma: Originates in the connective tissues or muscles of the vulva.
Signs & Symptoms
Recognizing the signs and symptoms of vulvar cancer early can significantly improve the chances of successful treatment. Here are the common signs and symptoms to watch out for:
→ Early Signs
- Persistent Itching: Chronic itching in the vulvar area.
- Skin Changes: Appearance of lumps, warts, or an open sore that does not heal.
- Color Changes: Changes in skin color (red, white, or darkened areas).
- Pain or Tenderness: Discomfort, burning sensations, or pain in the vulvar area.
→ Advanced Symptoms
- Bleeding or Discharge: Unusual bleeding or discharge not related to menstruation.
- Pain During Urination: Discomfort or pain while urinating, indicating possible spread to nearby tissues.
- Pain During Intercourse: Painful sexual intercourse can be an indicator of underlying issues.
- Lumps or Masses: Presence of a lump or mass in the vulvar area.
→ Importance of Seeking Medical Advice
If you experience any of these symptoms, it is crucial to Consult a Cancer Specialist as soon as possible. Early detection is key to effective treatment and improved outcomes. Even if the symptoms are subtle or seem unrelated, it’s better to err on the side of caution.

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Diagnostic Tests & Procedures
Early and accurate diagnosis is crucial in the effective treatment of vulvar cancer. At Kolhapur Cancer Centre, we utilize a comprehensive approach to ensure precise detection and staging of vulvar cancer. Here’s an overview of the diagnostic process:
→ Initial Consultation
The diagnostic journey typically begins with an initial consultation where you will discuss your symptoms, medical history, and any risk factors with a specialist. This step is essential for your doctor to understand your overall health and identify any warning signs of vulvar cancer.
→ Physical Examination
During a physical examination, your doctor will conduct a thorough examination of the vulvar area to check for any abnormalities. This exam may include:
- Visual Inspection: Using a magnifying device to look for changes in the skin, lumps, or sores.
- Manual Examination: Feeling for lumps or irregularities in the vulva and surrounding areas.
→ Imaging Tests
Imaging tests provide detailed pictures of the internal structures and help in identifying the extent of the cancer. Common imaging tests include:
- Ultrasound: An ultrasound probe is used to produce images of the pelvic organs.
- Magnetic Resonance Imaging (MRI): Provides detailed images using magnetic fields and radio waves.
- Computed Tomography (CT) Scan: Combines X-ray images taken from different angles to create a comprehensive picture of the pelvic area.
- Positron Emission Tomography (PET) Scan: Uses a small amount of radioactive material to highlight cancerous cells.
→ Biopsy
A definitive diagnosis of vulvar cancer is made through a biopsy, where a small sample of tissue is removed and examined under a microscope. Types of biopsies include:
- Punch Biopsy: A small, round piece of tissue is removed using a punch tool.
- Incisional Biopsy: A larger section of tissue is surgically removed.
- Excisional Biopsy: The entire lump or suspicious area is removed for examination.
→ Other Diagnostic Procedures
- Colposcopy: A colposcope (a magnifying device) is used to closely examine the vulva for abnormal areas that may require a biopsy.
→ Importance of Early Detection
Detecting vulvar cancer at an early stage significantly improves treatment outcomes. If you experience any symptoms or have risk factors associated with vulvar cancer, it is crucial to seek medical advice promptly. Early diagnosis allows for more effective treatment options and better prognosis.
Available Treatments for Vulvar Cancer
At Kolhapur Cancer Centre, we understand that every patient’s journey with vulvar cancer is unique. Our comprehensive treatment plans are tailored to meet the specific needs of each individual. Here are the primary treatment options available for vulvar cancer:
→ Surgery
Surgery is often the first line of treatment for vulvar cancer, especially in its early stages. The goal is to remove the cancerous tissue while preserving as much of the surrounding healthy tissue as possible. Types of surgical procedures include:
- Local Excision: Removal of the cancerous lesion and a small margin of healthy tissue around it.
- Vulvectomy: Partial or complete removal of the vulva, depending on the extent of the cancer.
- Lymph Node Dissection: Removal of nearby lymph nodes to check for the spread of cancer.
→ Radiation Therapy
Radiation therapy uses high-energy rays to target and kill cancer cells. It can be used as a primary treatment or in conjunction with surgery and chemotherapy. There are two main types:
- External Beam Radiation Therapy (EBRT): Delivers radiation from outside the body, focusing on the cancerous area.
- Brachytherapy: Involves placing radioactive material directly inside or near the tumor, providing a high dose of radiation to the cancer cells while sparing healthy tissue.
→ Chemotherapy
Chemotherapy involves the use of drugs to destroy cancer cells. It can be administered orally or intravenously and is often used when cancer has spread beyond the vulva.
Chemotherapy may be used in combination with other treatments to increase effectiveness. Common side effects include nausea, fatigue, hair loss, and increased susceptibility to infections.
→ Targeted Therapy
Targeted therapy uses drugs or other substances to precisely identify and attack cancer cells, usually while doing little damage to normal cells.
This treatment targets specific molecules involved in the growth and spread of cancer cells. It can be an option for advanced vulvar cancers that express certain genetic markers.
→ Importance of a Multidisciplinary Approach
Treating vulvar cancer often requires a multidisciplinary approach that includes gynecologic oncologists, radiation oncologists, medical oncologists, and other specialists.
This ensures that all aspects of the patient’s health are considered, and the most effective treatment plan is developed.
Most Common FAQs on Vulvar Cancer
What is vulvar intraepithelial neoplasia (VIN)?
Vulvar intraepithelial neoplasia (VIN) is a precancerous condition where abnormal cells are found on the surface of the vulvar skin. VIN is classified into different grades based on the severity of the abnormal cell changes. While not cancerous, VIN can develop into vulvar cancer if left untreated.
Can vulvar cancer be prevented?
While there is no guaranteed way to prevent vulvar cancer, certain measures can reduce the risk. These include getting vaccinated against HPV, practicing safe sex, quitting smoking, and regularly undergoing gynecological exams to detect any early changes or abnormalities.
How is HPV related to vulvar cancer?
Human Papillomavirus (HPV) is a significant risk factor for vulvar cancer. Certain strains of HPV, particularly HPV-16 and HPV-18, are known to cause changes in the vulvar cells that can lead to cancer. HPV is a common sexually transmitted infection, and vaccination can help reduce the risk.
Is vulvar cancer hereditary?
There is no strong evidence to suggest that vulvar cancer is hereditary. However, having a family history of other cancers, such as cervical or breast cancer, may indicate a higher risk of developing various types of cancers, including vulvar cancer.
What are the treatment options for recurrent vulvar cancer?
Treatment options for recurrent vulvar cancer may include additional surgery, radiation therapy, chemotherapy, or a combination of these treatments. The specific approach depends on the location and extent of the recurrence, as well as the patient’s overall health and previous treatments received.
Can vulvar cancer affect fertility?
The impact of vulvar cancer on fertility depends on the extent of the cancer and the treatments used. While vulvar cancer itself does not typically affect the reproductive organs directly, treatments such as extensive surgery or radiation may have implications for sexual function and fertility. Discussing fertility preservation options with your doctor prior to treatment is important for those concerned about future fertility.
Are there support groups available for vulvar cancer patients?
Yes, there are support groups and resources available for vulvar cancer patients. These groups provide emotional support, information, and a sense of community for those affected by vulvar cancer. Kolhapur Cancer Centre can help connect you with local and online support resources.
How often should I have follow-up appointments after treatment?
Follow-up schedules vary based on the individual case and treatment plan. Generally, follow-up appointments are more frequent in the first few years after treatment to monitor for any signs of recurrence. Your doctor will provide a personalized follow-up plan based on your specific needs.
What lifestyle changes can help during and after treatment for vulvar cancer?
Adopting a healthy lifestyle can support your overall well-being during and after treatment. This includes maintaining a balanced diet, engaging in regular physical activity, avoiding smoking, and managing stress. It’s also important to follow your doctor’s recommendations and attend all follow-up appointments.
Can vulvar cancer affect my sexual health?
Vulvar cancer and its treatments can impact sexual health and function. Surgery or radiation therapy may cause changes in the vulvar area, leading to discomfort during sexual activity. Open communication with your healthcare provider about any concerns can help manage and address these issues, and they can offer support and resources to help maintain sexual health.
Kolhapur Cancer Centre is here to support you with comprehensive care, from diagnosis to treatment and beyond. If you have any further questions or concerns, please don’t hesitate to reach out to our team of specialists.
Are there support groups available for vulvar cancer patients?
Yes, there are support groups and resources available for vulvar cancer patients. These groups provide emotional support, information, and a sense of community for those affected by vulvar cancer. Kolhapur Cancer Centre can help connect you with local and online support resources.
How often should I have follow-up appointments after treatment?
Follow-up schedules vary based on the individual case and treatment plan. Generally, follow-up appointments are more frequent in the first few years after treatment to monitor for any signs of recurrence. Your doctor will provide a personalized follow-up plan based on your specific needs.
What lifestyle changes can help during and after treatment for vulvar cancer?
Adopting a healthy lifestyle can support your overall well-being during and after treatment. This includes maintaining a balanced diet, engaging in regular physical activity, avoiding smoking, and managing stress. It’s also important to follow your doctor’s recommendations and attend all follow-up appointments.
Can vulvar cancer affect my sexual health?
Vulvar cancer and its treatments can impact sexual health and function. Surgery or radiation therapy may cause changes in the vulvar area, leading to discomfort during sexual activity. Open communication with your healthcare provider about any concerns can help manage and address these issues, and they can offer support and resources to help maintain sexual health.
Kolhapur Cancer Centre is here to support you with comprehensive care, from diagnosis to treatment and beyond. If you have any further questions or concerns, please don’t hesitate to reach out to our team of specialists.
Oral Cancer Specialists At KCC, Kolhapur
Gynaecological Cancers Specialists At KCC, Kolhapur

Dr Suraj Pawar, MCh(Onco)
Chairman & Managing Director | Surgical Oncologist & Robotic Surgeon with 24+ years of experience

Dr. Kiran G. Bagul
Chief Surgical Oncologist & Robotic Surgeon, with 10 years of experience.
Dr. Nilesh A Dhamne
Medical and Pediatric oncologist, Hemato-oncologist with 5+ years of experience.
