Gynec Cancers
Vaginal Cancer
Vaginal cancer is a rare type of cancer that forms in the tissues of the vagina, the muscular tube connecting the uterus to the outer genitals.
- ON THIS PAGE:
- Overview
- Signs & Symptoms
- Diagnosis
- Treatment
- FAQs
Overview of Vaginal Cancer
Vaginal cancer is a rare type of cancer that forms in the tissues of the vagina, the muscular tube connecting the uterus to the outer genitals.
It primarily affects women over the age of 60 but can occur at any age. The most common type is squamous cell carcinoma, which begins in the thin, flat cells lining the vagina. Another type is adenocarcinoma, which starts in the glandular cells.
→ How Does Vaginal Cancer Occur?
Cancer occurs when cells in the body begin to grow uncontrollably. In the case of vaginal cancer, this uncontrolled growth starts in the cells lining the vagina. These cancerous cells can invade nearby tissues and spread to other parts of the body (metastasize).
→ Factors Responsible for Vaginal Cancer
Several factors may increase the risk of developing vaginal cancer:
- Human Papillomavirus (HPV) Infection: A significant risk factor, HPV is a sexually transmitted infection.
- Age: Women over 60 are at higher risk.
- History of Cervical Cancer: Women who have had cervical cancer are at increased risk.
- Diethylstilbestrol (DES) Exposure: Women whose mothers took DES during pregnancy to prevent miscarriage are at higher risk.
- Smoking: Increases the risk of many cancers, including vaginal cancer.
- Weakened Immune System: Conditions or medications that suppress the immune system can increase risk.
→ Stages and Grades of Vaginal Cancer
- Stage I: Cancer is confined to the vaginal wall. Prognosis is generally good with a high survival rate.
- Stage II: Cancer has spread to the tissues around the vagina but not to the pelvic wall. Prognosis is still favorable with appropriate treatment.
- Stage III: Cancer has spread to the pelvic wall and/or nearby lymph nodes. Prognosis is more guarded, requiring more aggressive treatment.
- Stage IV: Cancer has spread to other parts of the body, such as the bladder, rectum, or distant organs. Prognosis is poor, and treatment focuses on managing symptoms and improving quality of life.
→ Grades of Vaginal Cancer
- Grade 1 (Low Grade): Cancer cells look similar to normal cells and grow slowly.
- Grade 2 (Intermediate Grade): Cancer cells look more abnormal and grow at a moderate rate.
- Grade 3 (High Grade): Cancer cells look very different from normal cells and grow quickly.
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Types of Vaginal Cancer
- Squamous Cell Carcinoma: The most common type, originating in the squamous cells lining the vagina.
- Adenocarcinoma: Originates in the glandular cells of the vagina.
- Melanoma: A rare type that starts in the pigment-producing cells.
- Sarcoma: Originates in the connective tissues or muscles of the vagina.
Signs & Symptoms
Recognizing the signs and symptoms of vaginal cancer early can significantly improve the chances of successful treatment.
While vaginal cancer is rare, it’s essential to be aware of the potential indicators and seek medical advice if you notice any changes in your body. Here are the common signs and symptoms to watch out for:
→ Early Signs:
- Abnormal Vaginal Bleeding: This includes bleeding between periods, after intercourse, or post-menopause.
- Unusual Vaginal Discharge: A watery, bloody, or foul-smelling discharge can be an early warning sign.
- Pain During Intercourse: Discomfort or pain during sexual activity may indicate an underlying issue.
- Pelvic Pain: Persistent pain in the pelvic area without any clear cause should not be ignored.
→ Advanced Symptoms:
- Lumps or Masses: Feeling a lump or mass in the vagina can be a sign of advanced cancer.
- Difficulty Urinating: Issues such as pain, burning, or frequent urination could indicate the cancer has spread to the bladder.
- Constipation: Persistent constipation or pain during bowel movements might suggest the cancer has spread to the rectum.
- Leg Swelling: Swelling in the legs can occur if cancer has spread to the lymph nodes, causing a blockage.
→ Importance of Seeking Medical Advice:
If you experience any of these symptoms, it is crucial to consult a Cancer Specialist as soon as possible. Early detection is key to effective treatment and improved outcomes. Even if the symptoms are subtle or seem unrelated, it’s better to err on the side of caution.
At Kolhapur Cancer Centre, our specialists are dedicated to providing comprehensive care and support. We encourage you to schedule a consultation if you have any concerns about your gynecological health.
Remember, timely medical intervention can make a significant difference in managing vaginal cancer.

Chhatrapati Shahu Cancer Research Foundation, Kolhapur
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Diagnostic Tests & Procedures
Early and accurate diagnosis is crucial in the effective treatment of vaginal cancer. At Kolhapur Cancer Centre, we utilize a comprehensive approach to ensure precise detection and staging of vaginal cancer. Here’s an overview of the diagnostic process:
→ Initial Consultation:
The diagnostic journey typically begins with an initial consultation where you will discuss your symptoms, medical history, and any risk factors with a specialist. This step is essential for your doctor to understand your overall health and identify any warning signs of vaginal cancer.
→ Physical Examination:
During a physical examination, your doctor will conduct a pelvic exam to check for any abnormalities in the vagina, cervix, uterus, and other reproductive organs. This exam may include:
- Visual Inspection: Using a speculum to look inside the vagina.
- Manual Examination: Feeling for lumps or irregularities in the pelvic area.
→ Imaging Tests:
Imaging tests are used to obtain detailed pictures of the internal structures of the pelvis. Common imaging tests include:
- Transvaginal Ultrasound: An ultrasound probe is inserted into the vagina to produce images of the pelvic organs.
- Magnetic Resonance Imaging (MRI): Provides detailed images using magnetic fields and radio waves.
- Computed Tomography (CT) Scan: Combines X-ray images taken from different angles to create a comprehensive picture of the pelvic area.
- Positron Emission Tomography (PET) Scan: Uses a small amount of radioactive material to highlight cancerous cells.
→ Biopsy:
A definitive diagnosis of vaginal cancer is made through a biopsy, where a small sample of tissue is removed and examined under a microscope. Types of biopsies include:
- Punch Biopsy: A small, round piece of tissue is removed using a punch tool.
- Incisional Biopsy: A larger section of tissue is surgically removed.
- Endoscopic Biopsy: Tissue is removed using an endoscope, a thin tube with a camera and tools, inserted into the vagina.
→ Other Diagnostic Procedures:
- Pap Smear (Pap Test): Though primarily used to detect cervical cancer, a Pap smear can sometimes identify abnormal cells that suggest vaginal cancer.
- Colposcopy: A colposcope (a magnifying device) is used to closely examine the vagina and cervix for abnormal areas that may require a biopsy.
→ Importance of Early Detection:
Detecting vaginal cancer at an early stage significantly improves treatment outcomes. If you experience any symptoms or have risk factors associated with vaginal cancer, it is crucial to seek medical advice promptly. Early diagnosis allows for more effective treatment options and better prognosis.
At Kolhapur Cancer Centre, we are committed to providing state-of-the-art diagnostic services and compassionate care to our patients.
If you have concerns about your gynecological health, don’t hesitate to reach out to our specialists for a thorough evaluation and personalized care plan.
Available Treatments for Vaginal Cancer
At Kolhapur Cancer Centre, we understand that every patient’s journey with vaginal cancer is unique. Our comprehensive treatment plans are tailored to meet the specific needs of each individual. Here are the primary treatment options available for vaginal cancer:
→ Surgery:
Surgery is often the first line of treatment for vaginal cancer, especially in its early stages. The goal is to remove the cancerous tissue while preserving as much of the surrounding healthy tissue as possible. Types of surgical procedures include:
- Local Excision: Removal of the cancerous lesion and a small margin of healthy tissue around it.
- Vaginectomy: Partial or complete removal of the vagina, depending on the extent of the cancer.
- Lymph Node Dissection: Removal of nearby lymph nodes to check for the spread of cancer.
→ Radiation Therapy:
Radiation therapy uses high-energy rays to target and kill cancer cells. It can be used as a primary treatment or in conjunction with surgery and chemotherapy. There are two main types:
- External Beam Radiation Therapy (EBRT): Delivers radiation from outside the body, focusing on the cancerous area.
- Brachytherapy: Involves placing radioactive material directly inside or near the tumor, providing a high dose of radiation to the cancer cells while sparing healthy tissue.
→ Chemotherapy:
Chemotherapy involves the use of drugs to destroy cancer cells. It can be administered orally or intravenously and is often used when cancer has spread beyond the vagina.
Chemotherapy may be used in combination with other treatments to increase effectiveness. Common side effects include nausea, fatigue, hair loss, and increased susceptibility to infections.
→ Targeted Therapy:
Targeted therapy uses drugs or other substances to precisely identify and attack cancer cells while minimizing damage to normal cells.
These therapies target specific molecules involved in cancer growth and progression. Targeted therapy is usually considered for advanced vaginal cancer or when other treatments are not effective.
→ Personalized Treatment Plan:
At Kolhapur Cancer Centre, we believe in a personalized approach to cancer treatment. Our multidisciplinary team of specialists—including oncologists, surgeons, radiologists, and supportive care providers—work together to develop a tailored treatment plan for each patient.
Factors such as the type, stage, and grade of cancer, as well as the patient’s overall health and preferences, are taken into account.
→ Potential Side Effects:
Each treatment option has potential side effects, and it is essential to discuss these with your healthcare team. They will provide you with strategies to manage side effects and support you throughout your treatment journey. Common side effects may include:
- Surgery: Pain, infection, and changes in sexual function.
- Radiation Therapy: Skin irritation, fatigue, and changes to the vaginal tissue.
- Chemotherapy: Nausea, vomiting, hair loss, and increased risk of infections.
- Targeted Therapy: Diarrhea, liver issues, and skin problems.
For more information or to address any further questions, please don’t hesitate to reach out at KCC Hospital
Most Common FAQ Vaginal Cancer
Can Vaginal Cancer Be Prevented?
While there is no guaranteed way to prevent vaginal cancer, certain measures can reduce your risk. These include getting vaccinated against HPV, practicing safe sex, avoiding smoking, and attending regular gynecological check-ups and Pap smears to detect any abnormalities early.
How Can Lifestyle Changes Help in Managing Vaginal Cancer?
Maintaining a healthy lifestyle can support your overall well-being during and after treatment. This includes eating a nutritious diet, staying physically active, avoiding tobacco and excessive alcohol consumption, and managing stress through mindfulness or counseling.
How Can Lifestyle Changes Help in Managing Vaginal Cancer?
Maintaining a healthy lifestyle can support your overall well-being during and after treatment. This includes eating a nutritious diet, staying physically active, avoiding tobacco and excessive alcohol consumption, and managing stress through mindfulness or counseling.
Will Vaginal Cancer Affect My Fertility?
Treatment for vaginal cancer can impact fertility, especially if the reproductive organs are affected. If you are concerned about fertility, discuss options such as egg or embryo freezing with your healthcare team before starting treatment. Fertility preservation methods can provide opportunities for future family planning.
What Does Follow-Up Care Look Like After Treatment for Vaginal Cancer?
Follow-up care is crucial to monitor for any signs of recurrence and manage any long-term side effects of treatment. This typically includes regular physical exams, imaging tests, and consultations with your healthcare team. Your doctor will provide a personalized follow-up care plan tailored to your needs.
How Can I Cope with the Emotional Impact of a Vaginal Cancer Diagnosis?
Receiving a cancer diagnosis can be overwhelming. It is important to seek emotional support through counseling, support groups, or talking to loved ones. Practicing stress-relief techniques such as meditation, yoga, or hobbies can also help you cope with the emotional impact.
Is It Safe to Have Sexual Intercourse During and After Treatment?
Your ability to have sexual intercourse during and after treatment may vary depending on the type of treatment and its effects on your body. It is essential to discuss any concerns with your healthcare provider. They can provide guidance on sexual health and recommend ways to address any discomfort or changes in sexual function.
What Should I Do if I Notice New Symptoms After Treatment?
If you experience any new or unusual symptoms after completing treatment, it is important to contact your healthcare provider immediately. Early detection of any recurrence or new health issues can lead to more effective management and better outcomes.
Our expert team at Kolhapur Cancer Centre is dedicated to providing you with the best possible care. They will guide you through your treatment options, help you make informed decisions, and support you every step of the way.
Regular follow-ups and monitoring are essential to ensure the effectiveness of the treatment and to address any concerns promptly.
We are committed to offering compassionate care and advanced treatment options to improve the quality of life and outcomes for our patients. If you or a loved one is facing a diagnosis of vaginal cancer, please reach out to our team for comprehensive support and personalized care.
Gynaecological Cancers Specialists At KCC, Kolhapur

Dr Suraj Pawar, MCh(Onco)
Chairman & Managing Director | Surgical Oncologist & Robotic Surgeon with 24+ years of experience

Dr. Kiran G. Bagul
Chief Surgical Oncologist & Robotic Surgeon, with 10 years of experience.
Dr. Nilesh A Dhamne
Medical and Pediatric oncologist, Hemato-oncologist with 5+ years of experience.
