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Buccal Mucosa Cancer
Buccal Mucosa Cancer refers to cancers that develop in the inner lining of the cheeks, known as the buccal mucosa.
- ON THIS PAGE:
- Overview
- Signs & Symptoms
- Diagnosis
- Treatment
- FAQs
Overview of Buccal Mucosa Cancer
Buccal Mucosa Cancer refers to cancers that develop in the inner lining of the cheeks, known as the buccal mucosa. This type of cancer typically begins in the squamous cells lining the inside of the mouth.
How Does It Happen?
Buccal Mucosa Cancer occurs when healthy cells in the inner cheek undergo genetic mutations. These mutations cause the cells to grow uncontrollably, forming a tumor. If not detected and treated early, the cancerous cells can invade nearby tissues and spread (metastasize) to other parts of the body.
Causes & Risk Factors
- Tobacco Use: Smoking cigarettes, cigars, pipes, or using smokeless tobacco.
- Excessive Alcohol Consumption: Heavy drinking is a major risk factor.
- Human Papillomavirus (HPV) Infection: Certain strains of HPV are linked to oral cancers.
- Poor Oral Hygiene: Chronic irritation from rough teeth or ill-fitting dentures and poor dental care.
- Sun Exposure: Prolonged exposure to the sun can increase the risk of lip cancer, which can extend to the buccal mucosa.
- Family History: A history of cancer in the family can increase risk.
- Age: Risk increases with age, particularly after 40.
Stages & Grades
- Stages:
- Stage I: Tumor is 2 centimeters or smaller and hasn’t spread to lymph nodes.
- Stage II: Tumor is between 2 and 4 centimeters and hasn’t spread to lymph nodes.
- Stage III: Tumor is larger than 4 centimeters or has spread to one lymph node.
- Stage IV: Tumor has spread to nearby tissues, lymph nodes, or distant organs.
- Grades:
- Grade 1 (Low Grade): Cancer cells resemble normal cells, indicating slower growth.
- Grade 2 (Moderate Grade): Cancer cells are moderately different from normal cells.
- Grade 3 (High Grade): Cancer cells look very different from normal cells and tend to grow and spread quickly.
Prognosis at Each Stage & Grade
- Stage I and II: High survival rates with early detection and treatment.
- Stage III: Moderate prognosis, with treatment focusing on controlling the spread.
- Stage IV: Lower survival rates, requiring aggressive treatment strategies.
Types of Buccal Mucosa Cancer
- Squamous Cell Carcinoma: The most common type, originating in the squamous cells.
- Verrucous Carcinoma: A rare, slow-growing type that is less likely to spread.
- Minor Salivary Gland Carcinomas: Cancers that start in the minor salivary glands within the buccal mucosa.
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Signs & Symptoms
- A sore or lump in the inner cheek that doesn’t heal
- White or red patches on the inner lining of the cheeks
- Persistent mouth pain
- Difficulty chewing or swallowing
- Loose teeth or dentures that no longer fit well
- A lump in the neck
- Unexplained weight loss
- Persistent bad breath
When to See a Specialist?
If you notice any of these symptoms persisting for more than two weeks, it is crucial to consult a specialist. Early detection significantly improves treatment outcomes. Contact KCC to schedule an appointment with our experts.

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Diagnostic Tests & Procedures
- Physical Examination: Inspection of the mouth and throat for abnormalities.
- Endoscopy: Using a flexible tube with a light and camera to examine the mouth and throat.
- Imaging Tests: X-rays, CT scans, MRI, and PET scans to determine the extent of the cancer.
- Biopsy: Removing a tissue sample for microscopic examination to confirm cancer.
- HPV Testing: Testing for the presence of HPV if throat cancer is suspected.
How Specialists Confirm the Diagnosis?
Specialists at KCC use a combination of physical examination, endoscopic findings, imaging results, biopsy findings, and HPV testing to confirm the diagnosis of Buccal Mucosa Cancer.
A biopsy provides definitive evidence by revealing the presence of cancer cells under a microscope. This process ensures that the diagnosis is accurate, guiding the specialists to develop an effective treatment plan tailored to your needs.
For more information, please contact KCC.
What to Do When Diagnosed?
Receiving a cancer diagnosis can be overwhelming, but you are not alone. At KCC, we offer comprehensive support, including personalized treatment plans, counseling, and access to support groups to help you navigate this challenging journey.
It’s essential to stay informed and proactive. Reach out to KCC to schedule a consultation and discuss the next steps with our expert team.
Available Treatments for Buccal Mucosa Cancer
- Surgery: The primary treatment for localized Buccal Mucosa Cancer, involving the removal of the tumor and surrounding tissues.
- Radiation Therapy: High-energy rays target and kill cancer cells, often used after surgery to eliminate remaining cancer cells.
- Chemotherapy: Drugs used to kill cancer cells, often combined with radiation therapy for advanced stages.
- Targeted Therapy: Drugs that target specific pathways involved in cancer growth.
- Immunotherapy: Boosts the immune system to fight cancer, used in certain cases.
Gold Standard Treatment & Why
Surgical resection combined with radiation therapy is considered the gold standard for early-stage Buccal Mucosa Cancer due to its potential for complete removal of the cancer and elimination of any remaining cancer cells. For advanced stages, a combination of therapies such as chemotherapy and targeted therapy may be employed.
Whom to Consult for Treatment
Consult our specialized oncologists, & surgeons at KCC. Our multidisciplinary team collaborates to provide comprehensive care tailored to your condition. Don’t wait—schedule a consultation with our team today.
Prognosis of Treatment
The prognosis of Buccal Mucosa Cancer depends on several factors, including the stage at diagnosis, lymph node involvement, and response to treatment. Early detection and prompt treatment significantly improve survival rates. Regular follow-ups are essential to monitor for any signs of recurrence. For detailed information on your specific prognosis, please contact KCC to speak with our specialists.
Most Common FAQs on Buccal Mucosa Cancer
What are the early symptoms of Buccal Mucosa Cancer?
Early symptoms include sores or lumps in the inner cheek, white or red patches, and persistent mouth pain.
How is Buccal Mucosa Cancer diagnosed?
Diagnosis involves physical examination, endoscopy, imaging tests, biopsy, and HPV testing.
Can Buccal Mucosa Cancer be prevented?
Prevention strategies include avoiding tobacco and excessive alcohol, maintaining good oral hygiene, and protecting lips from sun exposure.
Is Buccal Mucosa Cancer hereditary?
While most cases are not hereditary, a family history of cancer can increase risk.
What is the survival rate for Buccal Mucosa Cancer?
Survival rates vary, with higher rates for early-stage detection and successful treatment.
What are the treatment side effects?
Side effects depend on the treatment but may include fatigue, mouth sores, and difficulty swallowing
Can Buccal Mucosa Cancer recur?
Yes, regular follow-ups are essential to monitor for recurrence.
Are there alternative treatments for Buccal Mucosa Cancer?
Some patients explore complementary therapies, but always consult your doctor first.
How do I choose the right treatment plan?
Discuss options with your oncologist to determine the best plan for your specific case.
What support services are available at KCC?
KCC offers counseling, nutritional advice, and support groups for patients and families.
At Kolhapur Cancer Centre, we are dedicated to providing exceptional care and support to Buccal Mucosa Cancer patients. Contact us today to learn more about our services and how we can assist you on your journey to recovery. Get in touch with KCC to start your treatment journey.
Head and Neck Cancers Specialists At KCC, Kolhapur
Dr. Parag J. Watve
Medical Director & Chief Head & Neck Cancer Surgeon, with 10+ years of experience.
Dr. Aditi Saha
Consultant Head & Neck Surgical Oncology
Dr. Nilesh A Dhamne
Medical and Pediatric oncologist, Hemato-oncologist with 5+ years of experience.
